ACCS Practice Exam 2025 – Complete Test Preparation Guide

The proliferative phase of Acute Respiratory Distress Syndrome (ARDS) typically occurs approximately 7 to 10 days after the initial injury. Understanding the timeline of ARDS progression is crucial for managing the condition effectively.

During the initial phase, referred to as the exudative phase, there is damage to the alveolar-capillary membrane, leading to increased permeability, fluid accumulation, and impaired gas exchange. After several days, the body begins to repair this damage, entering the proliferative phase, characterized by the proliferation of type II pneumocytes and fibroblast activity. This phase includes the formation of granulation tissue and the resolution of edema, marking a shift toward recovery and repair in the alveoli.

Being aware of this timeline helps healthcare professionals anticipate the potential complications and guide interventions appropriately. Recognizing the proliferative phase helps in monitoring patients closely for signs of recovery or progression to fibrosis, which can severely impact respiratory function if not managed properly.